Latanoprost- ChongDa Prostaglandin Fine Chemicals Co., Ltd

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Latanoprost

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Min.Order:1 Vial(s)
Payment Terms:L/C , T/T

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ChongDa Prostaglandin Fine Chemicals Co., Ltd

Business Type:Manufacturer

Country/Region:China

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HOT Rank

6/10

Product Information

Chemical Formula:C26H40O5
Molecular Weight:432.59
Assay:94.0%~102%
Pharmacopeia:CP
Shelf Life:18 months
Storage:Sealed

Description

Latanoprost (PHXA41) is a prostaglandin F2α analogue and can be used for glaucoma research. Latanoprost can effectively pass through cornea and be hydrolyzed by esterase to latanoprost acid. latanoprost acid is an F-prostaglandin (FP) receptor agonist, and can effectively reduce intraocular pressure (IOP) by increasing the outflow of aqueous humor through uvea.

Appearance	colorless or light yellow Oil
Identification	A： IR B： The retention time of the major peak in the chromatogram of the sample corresponds to that of the standard solution, as obtained in the assay.
Solubility	Freely soluble in Isopropanoll and methanol
Residue on ignition	≤0.5%
Specific Rotation	+ 31° ~ + 38°
Water	≤ 2.0 %
Related substances	Isopropyl diphenylphosphorylpentanoate ≤ 0.1% Latanoprost related Compound B ≤ 0.5% Latanoprost related Compound A ≤ 3.5% Any other impurity： ≤ 0.1% Total impurities：≤ 0.5% LIMIT OF LATANOPROST RELATED COMPOUND E≤ 0.2%
Residue Solvent	n-Hexane：≤ 0.029% Ethanol： ≤ 0.5% Methanol：≤ 0.3% Isopropanol ≤ 0.5
Assay	94.0%~102%(calculated on the anhydrous and sol-vent-free basis)