Alprostadil

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ChongDa Prostaglandin Fine Chemicals Co., Ltd

Business Type:Manufacturer

Country/Region:China

Ddu Verified

HOT Rank

6/10

Product Information

  • Chemical Formula:C20H34O5
  • Molecular Weight:354.48
  • Assay:95.0%~102.5%
  • Pharmacopeia:CP
  • Shelf Life:18 months
  • Storage:Sealed

Description

Prostaglandin E1 (Alprostadil) is a prostanoid receptor ligand, with Kis of 1.1 nM, 2.1 nM, 10 nM, 33 nM and 36 nM for mouse EP3, EP4, EP2, IP and EP1, respectively. Prostaglandin E1 induces vasodilation and inhibits platelet aggregation. Prostaglandin E1 can be used as a vasodilator for the research of peripheral vascular diseases.

Appearance

White to off-white crystalline powder

Identification

HPLC retention time of sample complies with that of known sample

Specifific optical rotation

-60.0°~ -70.0°

Water

≤0.5%

Residue on Ignition

≤0.5%

Related Substances

Impurity A ≤1.5%
Impurity B ≤ 0.5%
Any other impurity ≤ 0.9%
Total impurities ≤1.5%

Residual solvents

Ethanol ≤5000ppm
Acetone ≤5000ppm
Dichloromethane ≤600ppm
n-Hexane ≤290ppm
Ethyl acetate ≤5000ppm
n-Heptane ≤5000ppm

Assay

95.0%~102.5%(anhydrous substance)


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